Overview of our Applications
MolecuNav’s proprietary fluorine chemistry platform transforms drug discovery, development, and manufacturing by enabling rapid, precise incorporation of ¹⁹F and ¹⁸F into small molecules, biologics, and delivery systems.
Small Molecule Applications
Our platform introduces ¹⁹F or ¹⁸F into small molecules, preserving structure and activity for real-time ADME tracking via PET, SPECT, MRI, or NMR. Rapid, selective fluorination eliminates complex synthesis steps, speeding up analog generation and drug discovery.
Biologics Applications
MolecuNav’s fluorination tags enable precise labeling of biologics like antibodies and peptides using click chemistry, maintaining function. Track pharmacokinetics and biodistribution with PET, SPECT, or NMR to streamline discovery, preclinical studies, and regulatory submissions.
Radiopharmaceuticals & Diagnostics
MolecuNav enables high-yield ¹⁸F incorporation in under five minutes, overcoming its short half-life. Create novel radiotracers for PET imaging to monitor drug localization and efficacy, accelerating diagnostic and theranostic development.
API Process Development & Manufacturing
Our technology simplifies fluorine-containing API synthesis with direct, selective fluorination, reducing costs and steps. It enhances scalability and consistency for early-phase and GMP production, optimizing manufacturing of ¹⁹F-containing small molecules.
Drug Delivery
Our dual-labeling tracks therapeutics and delivery vectors (e.g., liposomes, LNPs) via PET, SPECT, or NMR. Quantify loading, release, and tissue accumulation to optimize complex modalities like RNA delivery with minimal off-target effects.
Drug Repurposing & Target Discovery
Precision tagging reveals molecular interactions, enabling drug repurposing and target deconvolution. Track off-target effects and tissue distribution to identify new indications, diversifying pipelines with reduced regulatory risk.